Senyawa Senyawa Alkaloid Furokuinolin dari Kulit Batang Zanthoxylum acanthopodium DC

  • Tjitjik Tjahjandarie Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia https://orcid.org/0000-0003-0894-9803
  • Alfiah Nur Irza Gunawan Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia
  • Ratih Dewi Saputri Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia https://orcid.org/0000-0002-5982-8983
  • Mulyadi Tanjung Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia https://orcid.org/0000-0002-8252-6692
Keywords: skimmianin, antikanker

Abstract

Dua senyawa alkaloid furokuinolin, diktammin (1) dan skimmianin (2) telah berhasil diisolasi dari kulit batang Zanthoxylum acanthopodium DC. Penentuan struktur kedua senyawa alkaloid ditetapkan berdasarkan analisis spektrum UV, IR, MS, 1D dan 2D NMR. Uji aktivitas antikanker senyawa 12 terhadap sel murine leukemia P-388 memperlihatkan nilai IC50 10,41 dan 4,85 µg/ml.

 

 

Published
2019-12-31
How to Cite
Tjahjandarie, T., Irza Gunawan, A. N., Saputri, R. D., & Tanjung, M. (2019). Senyawa Senyawa Alkaloid Furokuinolin dari Kulit Batang Zanthoxylum acanthopodium DC. Jurnal Sains Dan Kesehatan, 2(2), 89-92. https://doi.org/10.25026/jsk.v2i2.121

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