Aspek Genetik Kanker Kolorektal

Authors

  • Andreliano Yosua Rompis Fakultas Kedokteran Universitas Udayana
  • Ni Nyoman Ayu Dewi Fakultas Kedokteran Universitas Udayana

DOI:

https://doi.org/10.25026/jsk.v2i3.145

Keywords:

genetik, kanker, mutasi

Abstract

Kanker kolorektal merupakan masalah kesehatan di dunia. Perkembangan kanker kolorektal memerlukan waktu panjang dan berkaitan dengan faktor lingkungan, genetik dan epigenetik. Patogenesis kanker kolorektal melibatkan tiga jalur yang seringkali tumpang tindih yaitu chromosomal instability (CIN), microsatellite instability (MSI) dan CpG island methylator phenotype (CIMP). Dalam tulisan ini dibahas mengenai kanker kolorektal herediter dan sporadik serta aspek genetiknya. Pemahaman mengenai aspek genetik kanker kolorektal sangat berperan dalam manajemen penyakit ini.

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Published

2020-06-30

How to Cite

Rompis, A. Y. ., & Ni Nyoman, A. D. (2020). Aspek Genetik Kanker Kolorektal. Jurnal Sains Dan Kesehatan, 2(3), 236–245. https://doi.org/10.25026/jsk.v2i3.145