Formulasi dan Evaluasi Serum Gigi Ekstrak Etanol Siwak (Salvadora persica L.)
Formulation and Evaluation of Dental Serum from Siwak Ethanolic Extract (Salvadora persica L.)
Keywords:Dental Serum, Siwak, Streptococcus mutans
Dental health is a common problem in society. Traditionally, siwak is used to prevent bleeding gums and has antimicrobial effects. In this study, a tooth serum was made from ethanol extract of siwak and its preparations were evaluated and its antibacterial effect was tested. The method used in this research was experimental and three formulations were made with different concentrations of ethanol extract of siwak, formulation 1 (21%), formulation 2 (42%), and formulation 3 (63%). The results of the preparation evaluation showed that the three formulations were not significantly different compared to the control based on organoleptic test, viscosity, pH, dispersion, and stability test. The antimicrobial effect test showed that the three formulations were able to inhibit streptococcus mutans. After the research, the conclusion that can be taken is that the three formulations of the tooth serum ethanol extract of siwak are pharmaceutically stable and formulation 3 showed the best antibacterial effect.
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