Hubungan Status Gizi, Umur, Jenis Kelamin dengan Derajat Infeksi Dengue pada Anak di RSUD Abdul Wahab Sjahranie Samarinda

Relationship between Nutritional Status, Age, Gender and Degree of Dengue Infection in Children at Abdul Wahab Sjahranie Hospital Samarinda

  • Putri Lintang Kharisma Program Studi Kedokteran Universitas Mulawarman https://orcid.org/0000-0002-7642-5561
  • Annisa Muhyi Laboratorium Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Mulawarman
  • Eva Rachmi Laboratorium Ilmu Anatomi Fakultas Kedokteran Universitas Mulawarman
Keywords: Nutritional status, age, sex, degree of dengue infection

Abstract

Dengue virus infection can manifest from mild to severe, which are undifferentiated fever, dengue hemorrhagic fever (DD), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), respectively. Mild and severe dengue infection is difficult to distinguish early in the course of the disease, and the clinical course is also difficult to "predict". Therefore, indicators were needed to predict the degree of dengue virus infection, thus appropriate treatment can be given. The study was aimed to determine the association of nutritional status, age, and sex with the degree of dengue infection in children. This study was an analytic observational study with a cross-sectional design. The samples were pediatric patients (0-18 years), who have been diagnosed with dengue virus infection and were hospitalized at the Abdul Wahab Sjahranie Hospital Samarinda in 2019. Purposive sampling technique was used to appointed 88 patients. The data obtained from the medical records. The bivariate association was statistically analyzed with chi-square test. The result showed a significant association between sex (p = 0.041) with the degree of dengue infection in children. Meanwhile nutritional status (p = 0.127) and age (p = 0.077) had no significant association with the degree of dengue infection in children. In conclusion, sex might serve as a predictor of the degree of dengue infection in children, in which male is more susceptible to worse manifestations.

References

[1] WHO. (2012). Global strategy for dengue prevention and control 2012-2020. Geneva: WHO Press.
[2] Indrayani, Y. A., & Wahyudi, T. (2017). Situasi Penyakit Demam Berdarah di Indonesia tahun 2017. Jakarta: Infodatin : Pusat Data dan Informasi Kementerian dan Kesehatan RI.
[3] WHO. (2011). Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever. New Delhi: World Health Organization.
[4] Kemenkes RI. (2018). Data dan Informasi Profil Kesehatan Indonesia. Jakarta: Kemenkes RI.
[5] Dinas Kesehatan Provinsi Kalimantan Timur . (2018). Profil Kesehatan Tahun 2017. Samarinda: Dinas Kesehatan Provinsi Kalimantan Timur.
[6] Yulianto, A., Laksono, I. S., & Juffrie, M. (2016, Oktober). Faktor Prognosis Derajat Keparahan Infeksi Dengue. Sari Pediatri, 198-203.
[7] Novrita, B., Mutahar, R., & Purnamasari, I. (2017). Analisis Faktor Risiko Kejadian Demam Berdarah Dengue di Wilayah Kerja Puskesmas Celikah Kabupaten Ogan Komering Ilir. Jurnal Ilmu Kesehatan Masyarakat, 19-27.
[8] Prasetya, D. I., Hadisaputro, S., Udji Sofro, M. A., Lukmono, D. T., & Martini. (2017). Faktor Karakteristik Klinis Host dan Sosiodemografik yang Berpengaruh Terhadap Kejadian Dengue Shock Syndrome. Jurnal Epidemiologi Kesehatan Komunitas, 99-108.
[9] Buntubatu, S., Arguni, E., Indrawanti, R., Laksono, I. S., & Prawirohartono, E. P. (2016). Status Nutrisi sebagai Faktor Risiko Sindrom Syok Dengue. Sari Pediatri, 226-232.
[10] Trang, N. T., Long, N. P., Hue, T. T., Hung, L. P., Trung, T. D., Dinh, D. N., Hirayama, K. (2016). Association Between Nutritional Status and Dengue Infection: A Systematic Review and Meta-analysis. BMC Infectious Disease, 1-11.
[11] Permatasari, D. Y., Ramaningrum, G., & Novitasari, A. (2015). Hubungan Status Gizi, Umur dan Jenis Kelamin dengan Derajat Infeksi Dengue pada Anak. Jurnal Kedokteran Muhammadiyah, 2, 24-28.
[12] Suryani, E. T. (2018, Desember 31). Gambaran Kasus Demam Bedarah Dengue di Kota Blitar tahun 2015-2017. Jurnal Berkala Epidemiologi, 6, 260-267.
[13] Vebriani, L., Wardana, Z., & Fridayenti, F. (2016, Februari). Karakteristik hematologi pasien demam berdarah dengue di bagian penyakit dalam RSUD Arifin Achmad Provinsi Riau periode 1 Januari-31 Desember 2013. Jurnal Online Mahasiswa FK, 3, 1-20.
[14] Bhatia, R., Dash, A. P., & Sunyoto, T. (2013). Changing epidemiology of dengue in South-East Asia. WHO South-East Asia Journal of Public Health, 2(1), 23-27.
[15] Salsabila, O., Shodikin, M. A., & Rachmawati, D. A. (2017). Analisis Faktor Risiko Terjadinya Sindrom Syok Dengue Pada Anak di RSD dr. Soebandi Kabupaten Jember. Journal of Agromedicine and Medical Sciences, 56-61.
[16] Harjatmo, T. P., Par'i, H. M., & Wiyono, S. (2017). Penilaian Status Gizi. Jakarta: Kemenkes RI.
[17] WHO. (2015). National Guidelines for Clinical Management of Dengue Fever. New Delhi: WHO Press.
[18] Konan, K. V., & Sanchez-Felipe, L. (2015). Lipids and RNA virus replication. HHS Public Access, 1-16.
[19] Gurnida, D. A. (2011). Imunonutrisi. Bandung: Pustaka Unpad.
[20] Angraini, D. I., & Ayu, P. R. (2014). The Relationship Between Nutritional Status and Immunonutrition Intake with Immunity Status. Jurnal Kedokteran Unila, 158-165.
[21] Ahmed, S., Finkelstein, J. L., Stewart, A. M., Kenneth, J., Polhemus, M. E., Endy, T. P., Mehta, S. (2014). Review Article: Micronutrients and Dengue. The American Society of Tropical Medicine and Hygiene, 1049-1056.
[22] Candra, A. (2010). Demam Berdarah Dengue: Epidemiologi, Patogenesis, dan Faktor Risiko Penularan. Aspirator, 2, 110-119.
[23] Novitasari, A., Ramaningrum, G., & P, D. Y. (2015). Jurnal Universitas Muhammadiyah Semarang, 1-7.
[24] Baratawidjaja, K. G., & Rengganis, I. (2014). Imunologi Dasar Edisi 11 (Cetakan ke-2). Jakarta: Badan Penerbit FKUI.
[25] IDAI. (2015). Buku Ajar Infeksi & Pediatri Tropis Edisi Kedua. Jakarta: Badan Penerbit IDAI.
[26] Zein, D. A. (2015). Demam Berdarah Dengue. Jurnal Universitas Diponegoro, 1-22
[27] Fitriani, T. A. (2016). Karakteristik Pasien Demam Berdarah Dengue pada Anak di RSUD Indramayu pada tahun 2015. JKKI Universitas Islam Indonesia, 1-18.
[28] Edwin, J., Budiarta, M. O., & Edward, K. (2019). Analisis Faktor Risiko Sindrom Syok Dengue pada Anak di Rumah Sakit Ibu Anak Bunda Aliyah Jakarta. Sari Pediatri, 109-114.
[29] Anker, M., & Arima, Y. (2011). Male–female differences in the number of reported incident dengue fever cases in six Asian countries. Western Pacific Surveillance and Response, 1-7.
[30] Muenchhoff, M., & Goulder, P. J. (2014). Sex Differences in Pediatric Infectious Diseases. The Journal of Infectious Diseases, 120-126
[31] Giefing-Kroll, C., Berger, P., Lepperdinger, G., & Grubeck-Loebenstein, B. (2015). How sex and age affect immune responses, susceptibility to infections, and response to vaccination. Aging Cell, 309-321. doi:10.1111/acel.12326
Published
2021-06-02
How to Cite
Kharisma, P. L., Muhyi, A., & Rachmi, E. (2021). Hubungan Status Gizi, Umur, Jenis Kelamin dengan Derajat Infeksi Dengue pada Anak di RSUD Abdul Wahab Sjahranie Samarinda. Jurnal Sains Dan Kesehatan, 3(3), 376-382. https://doi.org/10.25026/jsk.v3i3.288