Hubungan Obesitas dengan Komplikasi Maternal dan Luaran Perinatal

Association of Obesity with Maternal Complication and Perinatal Outcomes

  • Laily Mulyani Program Studi Kedokteran, Fakultas Kedokteran, Universitas Mulawarman
  • Novia Fransiska Ngo Laboratorium Obstetri & Ginekologi, Fakultas Kedokteran, Universitas Mulawarman
  • Riries Choiru Pramulia Yudia Laboratorium Ilmu Kesehatan Masyarakat, Fakultas Kedokteran, Universitas Mulawarman
Keywords: obesity, BMI, preeclampsia, gestational diabetes, preterm birth, fetal death, macrosomia


Obesity is a global health problem which numbers continue to increase from year to year. Obesity is a risk factor for maternal complications and adverse perinatal outcomes. This systematic review aims to evaluate the association of obesity with maternal complications and perinatal outcomes. This systematic review was conducted by searching for studies on databases such as Pubmed, Google Scholar, Science Direct or Clinical Key and the studies observed are studies published in 2016-2020 in Indonesian and English. The results of the study search were obtained as many as 74 studies and 31 studies that met the inclusion and exclusion criteria of the study. Of the 31 studies examined, there were 16 studies that analyzed the associtation between obesity and preeclampsia, 25 studies that analyzed the association between obesity and gestational diabetes, 16 studies that analyzed the association between obesity and preterm birth, 15 studies that analyzed the association between obesity and fetal death, and 19 studies that analyzed the association between obesity and macrosomia. Based on this systematic review it can be concluded that obesity was associated with the incidence of preeclampsia, gestational diabetes, preterm birth and macrosomia. But, obesity was not associated with perinatal mortality.


[1] Kemenkes RI, “Epidemi Obesitas Kementerian Kesehatan Republik Indonesia,” 2017.
[2] M. Ng, T. Fleming, M. Robinson, B. Thomson, N. Graetz, and C. Margono, “Global, Regional, and National Prevalence of Overweight and Obesity in Children and Adults During 1980-2013: A systematic analysis for the Global Burden of Disease Study 2013,” Lancet, pp. 766–781, 2014.
[3] Kemenkes RI Balitbangkes, “Riset Kesehatan Dasar (Riskesdas),” 2013.
[4] Kemenkes RI Balitbangkes, “Riset Kesehatan Dasar (Riskesdas),” 2018.
[5] D. Ocviyanti and M. Dorothea, “Masalah dan Tata Laksana Obesitas dalam Kehamilan,” J. Indones. Med. Assoc., 2018.
[6] I. Kutchi, P. Chellammal, and A. Akila, “Maternal Obesity and Pregnancy Outcome: in Perspective of New Asian Indian Guidelines,” J. Gynecol. India, 2020.
[7] C. Lockwood and E. G. Oh, “Systematic reviews : Guidelines , tools and checklists for authors,” Nurs. Heal. Sci., pp. 273–277, 2017.
[8] S. Alkaf, O. F. Ilhami, M. B. Azhar, N. Bernolian, and A. Melizah, “Maternal Obesity Increases Risk for Adverse Maternal Outcome at RSUP Dr. Mohammad Hoesin Palembang,” Indones. J. Obstet. Gynecol. Sci., 2020.
[9] P. Deruelle, E. Servan-Schreiber, C. Riviere, O., Garabedian, and F. Vendittelli, “Does a Body Mass Index Greater Than 25 kg/m Increase Maternal and Neonatal Morbidity? A French Historical Cohort Study,” J. Gynecol. Obstet. Hum. Reprod., 2017.
[10] L. Liu, H. Wang, Y. Zhang, J. Niu, Z. Li, and R. Tang, “Effect of Pregravid Obesity on Perinatal Outcomes in Singleton Pregnancies Following in Vitro Fertilization and The Weight-loss Goals to Reduce The Risks of Poor Pregnancy Outcomes: A REtrospective Cohort Study,” PLoS One, 2020.
[11] I. Melchor, J. Burgos, A. d Campo, A. Aiartzaguena, J. Gutierrez, and J. C. Melchor, “Effect of Maternal Obesity on Pregnancy Outcome in Women Delivering Singleton Babies: A Historical Cohort Study,” J. Perinad. Med., 2019.
[12] V. L. Short et al., “The Relationship Between Body Mass Index in Pregnancy and Adverse Maternal, Perinatal, and Neonatal Outcomes in Rural India and Pakistan,” Am. J. Perinatol., 2017.
[13] C.-C. Liang, M. CHao, S.-D. Chang, and S. Y.-H. Chiu, “Impact of Prepregnancy Body Mass Index on Pregnancy Outcomes, Incidence and Quality of Life During Pregnancy - An Observational Cohort Study,” Biomed. J., 2019.
[14] J. K. Durst, A. L. Sutton, S. P. Cliver, A. T. Tita, and J. R. Biggio, “Impact of Gestational Weight Gain on Perinatal Outcomes in Obese Women,” Am. J. Perinatol., 2016.
[15] L. Gaudet, Z. M. Ferraro, S. W. Wen, and M. Walker, “Gaudet, L., Ferraro, Z. M., Wen, S. W., & Walker, M. (2014). Maternal Obesity and Occurrence of Fetal Macrosomia: A Systematic Review and Meta-Analysis,” J. Biomed. Biotechnol., 2014.
How to Cite
Mulyani, L., Ngo, N. F., & Yudia, R. C. P. (2021). Hubungan Obesitas dengan Komplikasi Maternal dan Luaran Perinatal. Jurnal Sains Dan Kesehatan, 3(2), 343-350.