Medication Related Burden pada Pasien Gagal Ginjal Kronis di RSUD Kota Yogyakarta

Medication Related Burden in Patients with Chronic Kidney Failure at the Yogyakarta City Hospital

Authors

  • Woro Supadmi Fakultas Farmasi, Universitas Ahmad Dahlan, Jl. Prof. DR. Soepomo Sh, Yogyakarta, Indonesia 55164
  • Muhammad Muhlis Fakultas Farmasi, Universitas Ahmad Dahlan, Jl. Prof. DR. Soepomo Sh, Yogyakarta, Indonesia 55164
  • Ilham Bintang Agung Fakultas Farmasi, Universitas Ahmad Dahlan, Jl. Prof. DR. Soepomo Sh, Yogyakarta, Indonesia 55164

DOI:

https://doi.org/10.25026/jsk.v3i6.575

Keywords:

Keywords: Chronic kidney disease, medication related burden, adherence

Abstract

Chronic kidney disease (CKD) is a condition of chronic kidney function decline, progressive and irreversible. Treatment measures given to patients with chronic kidney disease depends on what stage obtained from treatment of comorbid conditions to renal replacement or hemodialysis. Prolonged drug consumption affects the burden of medication or medication related burden on patients. This study was conducted to determine  the relationship between treatment load and the level of adherence in patients with chronic renal failure in RSUD Kota Yogyakarta. This study was observational study with a cross-sectional design. The instrument used was in the form of LMQ questionnaire to determine medication related burden and questionnaire MARS to determine the adherence. Data were analyzed by  Spearman Test to determine the relationship between medication-related burden and patient compliance. The results showed that significant correlation between LMQ scores and MARS scores (correlation coefficient = -0.413, p = 0.001) and between VAS Score and MARS scores (correlation coefficient = -0.413, p = 0.001). The higher the medication related burden, the lower the patient's compliance.

References

DAFTAR PUSTAKA

1. Adikusuma, W., Perwitasari, D.A., Supadmi, W., 2014, Evaluasi Kepatuhan Pasien Diabetes Melitus Tipe 2 Di Rumah Sakit Umum Pku Muhammadiyah Bantul, Yogyakarta, Media Farmasi, Vol. 11: 208-220.
2. Agustini, R., 2010, Dampak dukungan keluarga dalam mempengaruhi kecemasan pada pasien penderita gagal ginjal kronis di Rumah Sakit Panti Rapih Yogyakarta, [Online], Sumber: http://skripsi-indonesia.com [Akses: 10 Oktober 2020].
3. Al-Kloub, M.I., A bed, M.A., Al Khawaldeh, O.A., Al Tawarah, Y.M., & Froelicher, E.S., 2014, Predictors of non-adherence to follow-up visits and deferasirox chelation therapy among Jordanian adolescents with Thalassemia major. Pediatric hematology and oncology, 31(7), 624-637.
4. Alya, M.K., 2019, Medication Related Burden pada pasien Thalasemia di Rumah Sakit Umum Pusat DR Hasan Sadikin Bandung, Skripsi, Fakultas Farmasi Universitas Padjadjaran, Bandung.
5. Anonim,2011, Interpretasi data Klinik, Kementrian Kesehatan Republik Indonesia, Jakarta.
6. Costa, E., Giardini, A., Savin, M., Menditto, E., Lehane, E., Laosa, O., Pecorelli, S., Monaco, A. and Marengoni, A., 2015, Interventional tools to improve medication adherence: review of literature. Patient preference and adherence, Volume 9, pp.1303-1314.
7. D’Agostino, T.A., Atkinson, T.M., Latella, L.E., Rogers, M., Morrissey, D., DeRosa, A.P. and Parker, P.A., 2017, Promoting patient participation in healthcare interactions through communication skills training: a systematic review. Patient education and counseling, Volume 100(7), pp.1247-1257.
8. Dipiro, J.T., Rotschafer, J.C., Kolesar, J.M., Malone, P.M.,Schwinghammer, T.L., wells,B.G., Burns, M.A.,2015, Pharmacotheraphy: principles and practice, the McGraw–Hill Companies, New York.
9. Faktul., 2009, Faktor Kepatuhan Pasien, [Online], Sumber: http://www.Bidanlia.kepatuhanpasien.html [Akses: 10 Oktober 2020].
10. Farida, Z., Wakhid, A. and Suwanti, S., 2018, Hubungan Lama Hemodialisa Dengan Tingkat Kecemasan Pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisa Di Rsud Ambarawa Dan Rsud Ungaran Kabupaten Semarang, Doctoral dissertation, Universitas Ngudi waluyo.
11. Elsous, A., Radwan, M., Al-Sharis, H. & Mustafa, A.A., 2017, Medications Adherence and Associated Factors among Patients wit Type 2 Diabetes Mellitus in the Gaza Strip, Palestine. Front Endocrinol, Volume 8, p. 100.
12. Eton, D.T., de Oliveira, D.R., Egginton, J.S., Ridgeway, J.L., Odell, L., May, C.R. and Montori, V.M., 2012, Building a measurement framework of burden of treatment in complex patients with chronic conditions: a qualitative study. Patient related outcome measures, Volume 3, pp.39-49.
13. Evadewi, P.K.R., Sukmayanti, L.M.K., 2013, Kepatuhan mengonsumsi obat pasien hipertensi di Denpasar ditinjau dari kepribadian tipe A dan tipe B, Jurnal Psikologi Udayana, 1(1): 32-42.
14. Gallacher, K., Morrison, D., Jani, B., Macdonald, S., May, C.R., Montori, V.M., Erwin, P.J., Batty, G.D., Eton, D.T., Langhorne, P. and Mair, F.S., 2013, Uncovering treatment burden as a key concept for stroke care: a systematic review of qualitative research. PLoS Med, Volume 10(6), p.e1001473.
15. Gnjidic, D., Tinett, M. & Alloreb, H.G., 2017, Assessing medication burden and polypharmacy: finding the perfect measure. Expert Rev Clin Pharmacol, Volume 10(4), pp. 345-347.
16. Hervinda, S., & Novadian, N., 2014, Prevalensi dan Faktor Risiko Penyakit Ginjal Kronik di RSUP Dr. Mohammad Hoesin Palembang Tahun 2012, Majalah Kedokteran Sriwijaya, 46(4), 275–281.
17. Imanishi, Y., Fukuma, S., Karaboyas, A., Robinson, B.M., Pisoni, R.L., Nomura, T., Akiba, T., Akizawa, T., Kurokawa, K., Saito, A. and Fukuhara, S., 2017, Associations of employment status and educational levels with mortality and hospitalization in the dialysis outcomes and practice patterns study in Japan. PLoS One, Volume 12(3), p.e0170731.
18. Jin, J., Sklar, G.E., Oh, V.M.S. & Li, a. S.C., 2008, Factors affecting therapeutic compliance: A review from the patient’s perspective. Ther Clin Risk Manag, 4(1), pp. 269-286.
19. Johnson, A.B., Sebastian, A., Sudulaguntla, A., Sabu, A.C., Meka, S., Nanjwade, B.K., 2016, Medication Adherence Rating of Patients with Hypertension in A Tertiary Care Hospital, World Journal of Pharmacy and Pharmaceutical Sciences, Vol. 5, Issue 2, 694-710.
20. Kamaluddin, R. and Rahayu, E., 2009, Analisis faktor-faktor yang mempengaruhi kepatuhan asupan cairan pada pasien gagal ginjal kronik dengan hemodialisis di RSUD Prof. Dr. Margono Soekarjo Purwokerto, Jurnal Keperawatan Soedirman, 4(1).
21. Katusiime, B., Corlett, S.A. & Krska, J., 2018, Development and Validation of a Revised Instrument to Measure burden of long-term medicine use: the Living with Medicines Questionnaire version 3. Patient Related Outcomes Measure, Volume 9, pp. 155-168.
22. Krska, J., Morecroft, C.W., Rowe, P.H. & Poole, H., 2014, Measuring the impact of long-term medicines use from the patient perspective. Int J Clin Pharm, Volume 36, pp. 675-678.
23. Kuntjojo, 2009,Psikologi Kepribadian. Universitas Nusantara Kediri, Kediri.
24. Lemeshow, S., Hosmer, D.W., Klar, J. & Lwanga, S.K., 1997,Besar Sampel dalam Penelitian Kesehatan, Yogyakarta: Gadjahmada University Press.
25. Mahler, C., Hermann, K., Horne, R., Ludt, S., Haefeli, W.E., Szecsenyi, J., Jank, S., 2010, Assessing reported adherence to pharmacological treatment recommendations. Translation and evaluation of the Medication Adherence Report Scale (MARS) in Germany, J Eval Clin Pract,16(3):574–579.

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Published

2021-12-31

How to Cite

Supadmi, W., Muhlis, M., & Agung, I. B. (2021). Medication Related Burden pada Pasien Gagal Ginjal Kronis di RSUD Kota Yogyakarta : Medication Related Burden in Patients with Chronic Kidney Failure at the Yogyakarta City Hospital. Jurnal Sains Dan Kesehatan, 3(6), 760–766. https://doi.org/10.25026/jsk.v3i6.575